COMEDISEOUL, COORDINATED WITH CARE.

Choosing well

Exosomes and stem cells in Korea: what is actually injected

Exosome and stem-cell treatments are a newer category, and the same words are used for quite different products. Before anything is injected, ask exactly what is in the vial, who made it, and what its approval status is. Treat confident claims with care.

COMEDI editorial · 2026-10-06 · 7 min read

What readers ask

“Are these actual stem cells being injected into my face?”
“Why is it so much more expensive than Rejuran?”

What can these labels mean?

In clinic menus, stem cell and exosome can describe very different things. Some products are derived from cell cultures but contain no living cells. Some describe exosomes, tiny particles released by cells. Some refer to procedures using your own tissue. They are not interchangeable, and a menu label alone does not tell you which one you are getting.

What the menu saysWhat it may actually beAsk
Stem cell treatmentA product made from stem-cell culture, without living cellsDoes this contain living cells, or not?
ExosomeParticles derived from cells, from a manufacturerWhich product and manufacturer?
Your own cellsA procedure using your fat or bloodIs this processed from my own tissue?
Stem cell IVAn infusion productWhat exactly is infused, and what is its approval status?
Common meanings to clarify

Why does regulatory status differ?

Rules on cell-derived products differ between countries, and the same product may be treated differently in Korea, the United States, the UK, Japan or Taiwan. Some products are approved as medical products for specific uses. Others are sold as cosmetics or for topical use but applied in clinics in other ways. We do not make claims about any product's effectiveness, and we suggest you treat strong claims cautiously, wherever they come from.

What does it cost compared with established boosters?

$355Exosome 5cc, Seoul list price
$495Stem-cell product injection 3cc, Seoul list price
$140–$250Rejuran Healer 2cc, Seoul list price

Newer categories often carry a premium. A higher price does not mean stronger evidence. If you are choosing between a newer product and a booster with a longer track record, ask the doctor why they recommend one over the other for your skin.

What exactly should you ask?

  1. 01

    What is the product?

    Name, manufacturer and whether it contains living cells.

  2. 02

    What is its status?

    Is it approved in Korea, and for what use? Is it used as approved?

  3. 03

    How is it given?

    Injection, microneedling, topical after a laser, or infusion.

  4. 04

    What would the doctor expect?

    Ask what they have seen in patients like you, and what they would recommend instead if this were not available.

  5. 05

    What are the risks?

    Infection, irritation, allergic reactions and anything specific to the product.

“What exactly is in the vial is a fair question for any injection, and a necessary one for this category.”

Who might want to skip it?

  • Anyone being told it is proven, permanent or a cure.
  • Anyone who cannot get a clear answer about what the product is.
  • Anyone pregnant or breastfeeding, or with an active infection in the area.
  • Anyone who would be happier with an established booster at a lower price.

What are the honest limits?

We do not assess the science of individual products here, and this article makes no claim that they work or do not work. Evidence in this area is still developing and product names change quickly. Our role is to make sure you know what you are being offered and that the clinic can answer plainly.

Read our exosome and stem-cell treatment guide

Read the guide

General information, not medical advice. Your doctor decides what suits you.

Quick answers

Are living stem cells injected in Korean skin clinics?

Often the products are derived from stem-cell culture and contain no living cells. Ask the clinic directly what the product contains.

Are exosome treatments approved?

It depends on the product and the country. Ask the clinic for the product name, manufacturer and approval status in Korea.

Are exosomes better than Rejuran?

We do not make that claim. They are different categories. Ask the doctor why they recommend one over the other for your skin.

Why is it more expensive?

Newer products often carry a premium. Price is not a measure of evidence.

Treatment guides

IF THIS IS YOUR CONCERN

Neck lines in Korea: what actually helps, from boosters to a neck liftNeck lines and crepey neck skinUnder-eye hollows and dark circles in Korea: what actually works for which kindTear troughs, under-eye hollows and dark circlesHair loss treatment in Korea: medication, scalp injections or a transplant?Thinning hair and hair lossSmile lines in Korea: filler, lifting or nothing at all?Smile lines (nasolabial folds)

More to read